Research indicates that CJC-1295 DAC peptides can promote sustained release of growth hormone, enabling investigation into their effects on muscle hypertrophy, fat loss, metabolic health, and potential anti-aging therapies.
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CJC-1295 DAC (Drug Affinity Complex) is a synthetic peptide that functions as a growth hormone-releasing hormone (GHRH) analogue. It has been designed to enhance the secretion of growth hormone by stimulating the pituitary gland.
Unlike traditional GHRH, CJC-1295 DAC has a modified structure that allows for a longer half-life, resulting in sustained release and prolonged effects. Researchers have shown interest in this compound due to its potential applications in muscle growth, fat loss, and anti-aging therapies.
Additionally, its unique properties may also contribute to improved recovery rates in various clinical settings. Further studies are ongoing to fully understand the implications and efficacy of CJC-1295 DAC in human health.
CJC-1295 DAC exerts its effects primarily through its interaction with growth hormone secretagogue receptors (GHS-R) located in the pituitary gland. Upon administration, CJC-1295 DAC binds to these receptors, stimulating the pulsatile secretion of growth hormone (GH).
The modified structure of CJC-1295 DAC includes a drug affinity complex that prolongs its action within the body, providing a sustained release of the peptide. This results in increased serum levels of GH, leading to an elevation in insulin-like growth factor 1 (IGF-1), a critical mediator of growth and anabolic processes.
By enhancing GH and IGF-1 production, CJC-1295 DAC promotes protein synthesis, reduces adipose tissue, and supports muscle hypertrophy.
Furthermore, the peptide’s longer half-life minimises fluctuations in GH levels, creating a stable environment conducive to various physiological improvements.
This mechanism underlines the therapeutic potential of CJC-1295 DAC in clinical and research settings aimed at optimising growth hormone dynamics.
Direct SARMs Germany also offers CJC-1295 no DAC peptides for sale, discover more about this peptide here.
PubChem CID: 56841945
Molecular Formula: C152H252N44O42
Molecular Weight: 3367.9 g/mol
Sequence: H-Tyr-D-Ala-Asp-Ala-Ile-Phe-Thr-Gln-Ser-Tyr-Arg-Lys-Val-Leu-Ala-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Leu-Ser-Arg-NH2
Source: PubChem
View our CJC-1295 DAC High-Performance Liquid Chromatography (HPLC) Certificate here.
Buy CJC-1295 DAC Peptide Vial from Direct SARMs Germany. Available in 2mg, 5mg, 10mg vials and kits including bacteriostatic water and syringes for reconstitution.
Buy CJC-1295 DAC and GHRP-6 Nasal Spray
Buy CJC-1295 DAC and GHRP-6 Nasal Spray for clinical research from Direct Sarms Germany, available in 15ml and 30ml bottles. This nasal spray blend combines two potent peptides to synergistically enhance growth hormone release through complementary mechanisms.
CJC-1295 DAC stimulates the pituitary gland with a long-lasting effect, while GHRP-6 mimics Ghrelin to boost appetite and hormone secretion.
Administered nasally, this duo allows for rapid absorption, bypassing the gastrointestinal tract for immediate effects. Their combined effects make them promising for research into hormonal therapies, muscle growth, fat loss, and anti-aging applications.
Direct SARMs Germany has an extensive range of peptide nasal sprays available for research. For more information, visit our designated nasal page.
Buy CJC-1295 DAC and HGH Fragment 176-191 Blend Peptide Vial
Buy CJC-1295 DAC and HGH Fragment 176-191 Blend Peptide Vial 2.5mg for research from Direct Sarms Germany. The blended peptide vial offers a powerful tool for researchers focused on optimizing growth hormone dynamics. CJC-1295 DAC stimulates growth hormone release for sustained levels, while HGH Fragment 176-191 promotes fat loss without sacrificing muscle mass.
Together, they support research in areas like muscle hypertrophy, fat reduction, and metabolic health. This combination simplifies administration, facilitating controlled studies and advancing understanding of their therapeutic potential in human health and performance enhancement.
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Where is the best place to buy CJC-1295 DAC?
Direct SARMs Germany is a reliable and trustworthy supplier to buy CJC-1295 DAC peptides from. They guarantee a purity of 99% for all their peptides and they can deliver worldwide.
What is DAC?
DAC, or Drug Affinity Complex, is a modification added to peptides like CJC-1295 to improve their pharmacological properties. This change enhances the stability and half-life of the peptide, allowing for sustained release of active compounds and less frequent dosing. DAC is particularly useful in clinical settings, helping to maintain stable hormone levels for optimal physiological outcomes.
What are the potential applications of CJC-1295 DAC in research?
CJC-1295 DAC has potential applications in various research areas, including muscle growth, fat loss, anti-aging therapies, and recovery mechanisms in clinical settings. Its ability to enhance growth hormone and IGF-1 levels makes it a valuable tool for studying anabolic processes and metabolic health.
Are there any known side effects or risks associated with CJC-1295 DAC use?
While CJC-1295 DAC is generally well-tolerated, potential side effects may include injection site reactions, transient changes in glucose levels, and, in some cases, increased water retention. Researchers are encouraged to monitor subjects closely for any adverse reactions during studies.
How should CJC-1295 DAC be stored?
CJC-1295 DAC should be stored in a cool, dry place, ideally at temperatures between 2-8°C (36-46°F), and protected from light. Once reconstituted, it is crucial to refrigerate the peptide and use it within the specified time frame to maintain stability and efficacy.
Is CJC-1295 DAC dangerous?
CJC-1295 DAC is considered safe in controlled research settings when used according to protocols, but it carries potential risks and side effects, such as injection site reactions and changes in blood glucose levels. Close monitoring for adverse reactions is essential due to its effects on hormone levels, and the long-term impacts are not fully understood. A thorough risk assessment and informed consent are necessary before clinical use to ensure participant safety.
Is CJC-1295 DAC legal?
Qualified professionals can buy CJC-1295 DAC peptides for research purposes only, for example, for laboratory experiments in vitro testing. However, use of this product as a therapeutic agent for human consumption often falls under stricter regulations and may require appropriate licensing or prescriptions. It is essential for potential buyers to verify local laws regarding peptide procurement and ensure compliance to avoid legal repercussions.
For more information, explore our latest blog posts dedicated to CJC-1295 DAC peptides.
Researchers looking to buy CJC-1295 DAC for their studies can find it available in various forms, including blends, CJC-1295 DAC nasal sprays (available in 15ml and 30ml spray bottles) and subcutaneous injections (for example pre-mixed pens and peptide vials). Buy CJC-1295 DAC from Direct SARMs Germany, a reputable supplier of high quality 99% pure peptides with fast shipping worldwide.
[1] A. Volpe, G. Coukos, A. Barreca, G. Giordano, P. G. Artini, A. R. Genazzani (1991) Clinical use of growth hormone-releasing factor for induction of superovulation – Human Reproduction, Volume 6, Issue 9, 1 October 1991, Pages 1228–1232.
[2] L Jetté, R Léger, K Thibaudeau, C Benquet, M Robitaille, I Pellerin, V Paradis, P van Wyk, K Pham, D P Bridon (2004) Human Growth Hormone-Releasing Factor (hGRF)1–29-Albumin Bioconjugates Activate the GRF Receptor on the Anterior Pituitary in Rats: Identification of CJC-1295 as a Long-Lasting GRF Analog – Endocrinology, Volume 146, Issue 7, 1 July 2005, Pages 3052–3058.
[3] S L Teichman, A Neale, B Lawrence, C Gagnon, J-P Castaigne, and L A Frohman (2005) Prolonged stimulation of growth hormone (GH) and insulin-like growth factor I secretion by CJC-1295, a long-acting analog of GH-releasing hormone, in healthy adults – J Clin Endocrinol Metab, 2006 Mar; Volume 91 (Issue 3), Pages 799-805.
[4] Xiang-Bin Xu 1, Jin-Jiang Pang, Ji-Min Cao, Chao Ni, et al (2005) GH-releasing peptides improve cardiac dysfunction and cachexia and suppress stress-related hormones and cardiomyocyte apoptosis in rats with heart failure – American Journal of Physiology: Heart and Circulatory Physiology, 2005 Oct, Volume 289 (Issue 4), Pages H1643-51.
[5] Madalina Ionescu and Lawrence A. Frohman (2006) Pulsatile Secretion of Growth Hormone (GH) Persists during Continuous Stimulation by CJC-1295, a Long-Acting GH-Releasing Hormone Analog – The Journal of Clinical Endocrinology & Metabolism, Volume 91, Issue 12, 1 December 2006, Pages 4792–4797.
[6] M Alba, D Fintini, A Sagazio, B Lawrence, JP Castaigne, L A Frohman, R Salvatori (2006) Once-daily administration of CJC-1295, a long-acting growth hormone-releasing hormone (GHRH) analog, normalizes growth in the GHRH knockout mouse – American Journal of Physiology. Endocrinology and Metabolism, 2006 Dec, Volume 291 (Issue 6), Pages E1290-4.
[7] John Henninge 1, Milaim Pepaj, Ingunn Hullstein, Peter Hemmersbach (2010) Identification of CJC-1295, a growth-hormone-releasing peptide, in an unknown pharmaceutical preparation – Drug Testing and Analysis, 2010 Nov-Dec, Volume 2 (Issue 11-12), Pages 647-50.
[8] M C Van Hout and E Hearne (2016) Netnography of Female Use of the Synthetic Growth Hormone CJC-1295: Pulses and Potions – Substance Use and Misuse, 2016 Jan 2, Volume 51 (Issue 1), Pages 73-84.
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